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10 mg vial + 3 mL bacteriostatic water 10 mg 3 mL = 3.33 mg/mL At this concentration the same 0.25 mg starting dose becomes 0.25 3.33 = 0.075 mL 7.5 units , and the 2.4 mg maintenance dose becomes 2.4 3.33 = 0.72 mL = 72 units
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Recruitment of this complex is associated with increased expression of CCL3 ( Therefore, the severe form of COVID-19 induces hypomethylation of a CpG locus in the regulatory region of CCL3 , which is coherent with its upregulation
