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In aortic rings with intact endothelium, the hydroalcoholic extract exhibited a significant vasodilatory effect at concentrations ranging from 30 to 1000 g/mL, which was completely inhibited by soluble NOS and GC inhibitors

Indeed, experimental analysis showed that introduction of doxorubicin into physiologically relevant pH media yielded a concentration-dependent oxygen consumption profile, revealing free (non-metal catalysed) auto-oxidation (Fig

The risk of atherosclerotic disease was strongly associated with elevated homocysteine levels
Springer, Dordrecht