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Guo J, Yang G, He Y, Xu H, Fan H, An J, Zhang L, Zhang R, Cao G, Hao D, Yang H (2021) Involvement of 7nAChR in the protective effects of genistein against -amyloid-induced oxidative stress in neurons via a PI3K/Akt/Nrf2 pathway-related mechanism

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When synaptic depolarization occurs (typically through AMPAR activation), the driving force for Mg 2+ entry is reduced and the ion is expelled from the pore, thereby relieving the block and allowing current to flow (Nowak et al., 1984

Based on the selected literature, we summarize the pathogenic mechanisms of DKD and elucidate the therapeutic effects and mechanisms of bioactive substancesincluding polyphenols, peptides, polysaccharides, and flavonoidsin its treatment