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Description
Brensocatib has also been shown to reduce bone marrow NSP levels, and significantly improve disease score, in two rodent models of rheumatoid arthritis (198)
Wake et al., 2015
PMID 27126547
Toll-like receptors 2 and 4 (TLR-2/4) and cyclo-oxygenase 2 (COX-2) regulate microglial activation, which is crucial for the neuroinflammatory response
