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Three cell populations matter most for hair: dermal papilla cells (the population at the base of the follicle that orchestrates the growth cycle), keratinocytes (the cells that build the hair shaft itself), and fibroblasts (the connective-tissue cells that support the surrounding scalp matrix)
Upon stimulation with phenylephrine, both subtypes induce rapid phosphorylation of ERK1/2 through activation of PKC, which leads to ERK1/2 translocation to the nucleus
Is NNMT similar to NAD+
