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Diffuse axonal brain injury and traumatic brain injury A diffuse axonal brain injury (DAI) is a severe form of traumatic brain injury (TBI) characterized by widespread damage to the brains nerve fibers, known as axons

Similarly, deficiency of aldose reductase resulted in reduced oxidative stress in the peripheral nerves of diabetic mice (Ho et al., 2006)

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However, in recent years, current treatments have been shown to have a significant impact on oxidative pathways and can reverse pro-oxidative states in schizophrenia (127)
