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Its involvement in these processes underscores its significance in ensuring the proper progression of spermatogenesis, from the early stages of germ cell development to the maturation of spermatozoa [124,128]

Although fatigue and fatigability essentially result from a central phenomenon (since MS is a disease of the central nervous system), there are some central al peripheral factors to take into consideration when exploring the phenomenology of fatigue

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doi: 10.1016/j.rbmo.2014.02.004
