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Identification of Mycotoxin-Related Oxidant Stress OTA causes a variety of toxic presentations in animals with renal toxicitya prominent and consistent finding [69,70]with these cells showing inhibition of protein synthesis [71], impairment of energetic metabolism and changes in cell phenotype in renal cells [72], as well as increased oxidative stress [24,26,72]

For example, it reduces 7-ketocholesterol-induced endothelial damage, suppresses pro-inflammatory cytokines, and preserves tight junction protein integrity in a brain microvascular endothelial hCMEC/D3 cell line [20]

Lysophosphatidylcholine-induced elevation of asymmetric dimethylarginine level by the NADPH oxidase pathway in endothelial cells