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coupled polyethylene glycol (PEG) with PAMAM or PEI, which could mitigate their toxicity, and then evaluated biodistribution in a healthy mouse model, which was measured to be highly active and safe[84]
Youssef P., Hughes L., Kim W
How It Works (The Science): Unlike drugs like sildenafil which work on peripheral blood flow, PT-141 works directly on the brain's libido pathways
When using clarified cell lysates, each lysate was added to 5% of the reaction volume
