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The levels of most apolipoproteins and lipoproteins are regulated by various genes, which control not only the synthesis, secretion, and metabolism of apolipoproteins but also the size, number, and metabolic pathways of lipoprotein particles in the body
To test the role of the lid loop as a selectivity determinant, the LPLA2-N213Q/R214G mutant was assayed for cholesterol acyltransferase activity
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