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Our experimental and simulation data support a mechanism by which the brush sterically excludes the antibody, suggesting that our synthetic antigen sensors act as direct reporters of crowding heterogeneities with nanometer resolution

Finally, to further characterize the interaction between HuR and intron 14, we evaluated the region around the acceptor splicing site of intron 14 using publicly available photoactivatable ribonucleoside-enhanced cross-linking and immunoprecipitation (PAR-CLIP) data 27,58

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