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Franciszkowicz M

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GSH has been shown to act as a reductive co-substrate for GPX4, inducing GPX4 inactivation and thereby triggering ferroptosis in tumour cells

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P.Cys282Tyr homozygous females have a 1.3- to twofold increased risk of colorectal cancer, breast cancer, and arthritis compared to those without HFE gene pathogenic variants [25, 53]

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