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4,895,979, EP-A-339764, EP- B-295109, and Tetrahedron Letters, (1998) 29: 1555)

Clinical study on polycystic ovary syndrome treated with diane-35 and pioglitazone

87 Moreover, -alanine, a non-essential amino acid structurally similar to lactate, suppresses breast cancer tumorigenesis by competing with lactate for binding to AARS1 to interfere with p53 lactylation
In addition, betaine can also be synthesized de novo from dietary choline in the mammalian liver and kidney via a two-step enzymatic process in which choline is first oxidized to betaine aldehyde by choline dehydrogenase
