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For example, NCCN guidelines have noted that a psychostimulant can be offered, preferably for a time-limited trial, in refractory cases particularly in advanced cancer or end-of-life settings where immediate fatigue relief is a priority [54]

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Grace S, Pace R, Wydrzynski T: Formation and decay of monodehydroascorbate radicals in illuminated thylakoids as determined by EPR spectroscopy