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However, plant bioencapsulated protein have been shown to be effective at very low doses (0.15g/dose) in mice [52], highlighting the advantage of bioencapsulation in protecting the antigen from degradation in the digestive system prior to crossing the gut epithelium for delivery to target cells

Note: Sequence details can vary by reference and should be confirmed from the lot-specific CoA to ensure accuracy for your protocol

6 Currently, no cure exists for IBD, and treatment focuses on achieving and sustaining remission of inflammatory flares

In some embodiments, the otic formulation or composition comprises about 0.01% to about 1% by weight of the viscosity modulating agent(s)