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Description
Pregnancy and breastfeeding: There is insufficient safety data for peptide use during pregnancy or lactation
The 2006-2007 Phase 2 lipodystrophy trial was halted after a participant died
In a small-animal model of arthritis, zonulin acted as a disruptor of the tight junction barrier by reducing expression of occludin and ZO-1, associated with increased intestinal permeability to macromolecules (48)
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