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Patients with FR-positive platinum-resistant advanced-stage epithelial ovarian, primary peritoneal, or fallopian tube cancers were randomized to receive chemotherapy (paclitaxel, PLD, or topotecan) or mirvetuximab soravtansine

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The surviving cells or organisms are then bred, followed by the characterisation of the genetic determinants of the resulting enhanced radioresistance phenotype and the subsequent clinical translation of such genetic determinants to humans via multiplex genetic engineering

For the affinity chromatography at low pressure, nonrigid gels with large particle size are generally used as support materials while materials with small, rigid particles or synthetic polymers which are stable under high pressure and flow rates are used in high performance affinity applications [8,12]