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Current PL inhibitors and their efficacy The rising global incidence of obesity is an urgent public health issue linked to numerous metabolic diseases, including type 2 diabetes, heart disease, and some cancers
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Lipid biosynthesis coordinates a mitochondrial-to- cytosolic stress response
doi: 10.1093/nar/gkae973 Summary Keywords atheroscelrosis, cholesterol metabolism, acetyl-L-carnitine (ALC), SREBP2, HMGCR Citation Xing J, Du Z, Li F, Wang Y, Zhang Z, Gao X, Han L, Sun X, Sun H, Du Y, Hu C, Yu H and Qin Y (2024) Acetyl-L-carnitine ameliorates atherosclerosis in LDLR / mice by modulating cholesterol metabolism through SREBP2-dependent cholesterol biosynthesis
