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Prediction ability was assessed by the area under the ROC curve (AUC)

The mechanisms described above imply the activation of the signaling pathways characteristic for muscle metabolism: CPs raise the expression of the proteins: AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1) and phosphoinositide 3-kinase (PI3K) ( In addition, CPs might also influence the composition of gut microbiota, and correlation analyses suggest that there were up-regulated beneficial bacteria (such as Lactobacillus and Akkermansia ) upon supplementation with CP ( 4.5 Pea peptides: low allergenicity for special populations Pea peptides have lately become a good choice for those with certain diet restrictions mainly because they have low allergenicity (Figure 2)

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Good candidates for the combination Researchers already using tirzepatide who have plateaued represent the strongest candidates