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Description
There are three main pathways employed by hepatocytes to metabolize ethanol and all produce ROS
FTIR spectra were recorded from 750 cm 1 to 4000 cm 1 with a spectral resolution of 4 cm 1
Common features of this dysfunction include impaired oxidative phosphorylation, increased ROS production, mitochondrial DNA damage, and altered organelle dynamics
The silencing resulted in a substantial decrease in XPF protein levels, and, interestingly, also in the protein levels of its heterodimer partner ERCC1, suggesting that XPF is needed to maintain the stability of ERCC1 and prevent its degradation (Fig
