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Intramuscular administration of CoQ10, administered at a dose of 20 mg/kg (as a 1% solution in Tween 80), was described by Eleawa et al

Carotenoids may serve as an affordable means of prevention and potentially as a treatment, although human intervention trials have yielded mixed results, with some positive findings, many null findings, and some indications of harm in high-risk populations
doi: 10.3969/j.issn.1673-5374.2013.21.009

The red arrows in Figure 1 show what we call long-range interactions, in which substrates allosterically affect distant enzymes in the network
