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Unlike expression of the L858R-EGFR, expression of the L858R/T790M double-mutant receptor reduced intracellular GSH levels (Figure 4b)

While medications like statins, beta blockers, and ACE inhibitors have their place, they do not address the root causes of endothelial dysfunction, inflammation, or vascular injury

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The oxidant-scavenger theory of NAC action suggests that the free sulfhydryl group in NAC is an effective scavenger of one- and two-electron oxidants, such as H 2 O 2 , hypochlorous acid (HOCl), or hydroxyl radicals (OH)
