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Recommended dose should not be exceeded
Since poor absorption can be a problem with vitamin B12 which is the largest and most structurally complicated of the B vitamins patients need a formula that that can circumvent the stomach so that the B12 can efficiently reach the blood stream
However, cross-activation within MMPs and other proteases can remove the binding between the cysteine and the Zn + , resulting in a cysteine switch and subsequent MMP activation [27, 28]
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