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glutathione biosynthesis e coli Biological Databases and Tools - Metabolism in E. K-12 MG1655 Comprehensive elucidation of glutathione import
Description
A.Jr.BercuB

Orotidylate carboxylase, encoded by URA3, is an enzyme that is necessary for the de novo biosynthesis of pyrimidines converting orotidine-5-P to UMP (Fig 13) [215]

The dimer interface is formed by the interaction between loop 2 of one monomer and loop 1 of the other, stabilized by hydrogen bonds and salt bridges, resulting in a more open and flexible active site pocket compared to other GCTs

coli glutathione S-transferase (GST), a virulence factor implicated in detoxification and antibiotic resistance
