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Description
N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E (2) to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice

The first of these reactions is a transmethylation reaction, from which homocysteine is obtained as product

Selective Ferroptosis inhibitor Liproxstatin-1 attenuates neurological deficits and Neuroinflammation after subarachnoid hemorrhage

Maimone TJ
