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Source: Sonthalia et al., 2016 It works
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Supplemental creatine may reduce the need to manufacture creatine from SAM, conserving methyl groups and reducing SAH generation from endogenous creatine synthesis

Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum

The second hypothesis (which is not mutually exclusive) is that mitochondrial malfunction is what causes the loss of SNpc DA neurons in PD
