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Finally, some drugs or natural compounds have been reported to have antitumor properties by targeting metabolic vulnerabilities such as alterations in glycolysis, OXPHOS, and glutamine metabolism [13]

Since the 1970s, a plethora of epidemiological studies and clinical trials focusing on selenium supplementation have lent credence to the selenium cancer hypothesis. This hypothesis posits that a diet low in selenium associated with an elevated risk of developing cancer

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A meta-analysis of association between glutathione S-transferase M1 gene polymorphism and Parkinson's disease susceptibility