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Hyperthyroidism occurs due to metabolic impacts, autoimmune mechanisms, and gastrointestinal changes caused by the overproduction of thyroid hormones

Furthermore, the credibility of the findings should be regarding the possibility that the final endpoint of these concepts (cytoprotection organoprotection [41,42,43,44,45,46,47,48,49], reestablished body homeostasis [59,60,61]), response as such as claimed by both Robert and Selye [41,59], could ever be realized by the pharmacologic agent

Given the short half-life, twice-daily dosing provides additional exposure compared to once-daily protocols at the same total dose

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