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NNMT is upregulated in the white adipose tissue of obese animals and humans, and its activity is mechanistically linked to depleted cellular NAD+ and SAM pools

Baseline characteristics were collected and reviewed, including age, sex, height and weight, residence, the position of fracture, type of fracture, fractures history, smoking and alcoholism history, hip fracture type, polytrauma, surgical procedures, anesthesia, time from injury to surgery, electrocardiogram and chest radiograph, hemoglobin (Hb), international normalized ratio (INR), blood glucose (GLU), albumin (ALB), superoxide dismutase (SOD) and glutathione reductase (GR)

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Varieties of CKRT include continuous venovenous haemofiltration (CVVH), continuous venovenous haemodiafiltration (CVVHDF) and hybrid therapy