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From a market perspective, the demand for antifungal drugs continues to rise: The market is expected to expand at a compound annual growth rate (CAGR) of 2.81% from 2020 to 2033, with a size of 14.09 billion US dollars in 2024, expected to rise to 14.48 billion US dollars in 2025, and reach 18.08 billion US dollars by 2033 ( Figure 1 ) (Insights, 2025).However, the development and application of antifungal drugs face numerous challenges (Fisher et al., 2018

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Safety and efficacy of pridopidine in patients with Huntingtons disease (PRIDE-HD): a phase 2, randomised, placebo-controlled, multicentre, dose-ranging study

326,327 Quercetin activates Nrf2/Keap1 to reduce ROS, 328 while inducing ROS-dependent cell death in malignant cells, 329,330 underscoring its potential as both a chemopreventive and chemotherapeutic agent