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By acting as a potent Nrf2 agonist, sulforaphane chemically modifies the Keap1 repressor protein, allowing Nrf2 to flood into the cell nucleus
Oxaliplatin induces the PARP1-mediated parthanatos in oral squamous cell carcinoma by increasing production of ROS
Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease
In addition, IGF-2, whose expression normally is strictly controlled by parental imprinting is upregulated and functions as an important stimulant of the IGF-1R in cancer (LeRoith and Roberts, 2003)
