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The kinetic constants (K M and V max ) were calculated by fitting the data to the Michaelis-Menten equation in Prism version 6.0c for Mac (GraphPad Software, La Jolla California USA, www.graphpad.com)

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doi: 10.1038/s41586-020-2668-z 18 WilkinsonNPantopoulosK

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Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease

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