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Description
As will be discussed, one mechanism which may connect thiol-metal binding to oxidative stress-mediated toxicity is specific of Hg, the cysteinyl-glycine bound form of which is able to deplete glutathione reservoirs by a catalytic process [34]

Food Nutr Bull 2008;29:S238-44

When MTR activity is compromised by defective vitamin B12 binding or availability, it disrupts the folate cycle and hinders the rapid proliferation of cancer cells [185]

wherein R114 is substituted with either a K, or H
