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[278] discovered that long-term alcohol consumption can lead to significant changes in the composition and structure of the microbiota in the colon

Sanyal AJ, Campbell-Sargent C, Mirshahi F et al (2001) Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities
Additionally, strains resistant to other antibiotics like chloramphenicol and oxacillin are prevalent