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21 (Suppl 3): S3S6

In case reports of baclofen tolerant patients with intractable spasticity, intrathecal ziconotide administration in increasing doses made them spasm free [126]

furthermore, measurements in post-mortem conditions are subject to GSH breakdown (Perry et al., 1981), complicating interpretations and comparison to in vivo GSH levels

The active binding sites of the ligand should be accessible to the components of the mixture for easy binding, and the binding sites should not be deformed during the immobilization of the ligand to the solid support
