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Melanin Index Reduction In randomized, double-blind, placebo-controlled clinical trials, dermatologists monitored the skin changes of participants using a specialized spectrophotometer to track their Melanin Index (MI)

If the vial had instead been diluted with only 2mL, the concentration doubles to 10,000mcg/mL, and the same dose would require just 0.25mL (25 units)

Furthermore, the AMPK/PPAR coactivator-1 (PGC1) pathway upregulates autophagy-related genes, thereby promoting autophagy and phagosome fusion in macrophages during M.tb infection [116]