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Tumor necrosis factor (TNF) similarly impairs ABCA1-mediated efflux and sterol-O-acyltransferase 1 (SOAT1)-dependent cholesterol esterification through an NFATc1-dependent mechanism, promoting apoptosis (65)
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Oxidation of LDL in vitro has been used extensively to study the biological activities of oxLDL, but, even here, the actual species present varies significantly based on the oxidation method (exposure to air, to copper, or to oxidases) and length of oxidation
Volpi, E., Nazemi, R., & Fujita, S
