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The lack of fiber leads to increased bowel wall strain to move stool through the colon

Niacin is a necessary cofactor in the anabolic methionine cycle, supporting enzymes like dihydrofolate reductase

In addition to ferritin, PCBP1 and PCBP2 can also deliver iron to proteins that require nonheme iron as a cofactor or bind to ferroportin (Fpn) to remove excess Fe 2+ from cells

Dapagliflozin ameliorates renal tubular ferroptosis in diabetes via SLC40A1 stabilization
