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[DOI] [PubMed] [Google Scholar] 54.Chernysheva O.I., Bobyntsev I.I., Dolgintsev M.E

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Dual inhibition of the MEK-ERK pathway (classical tumor signaling pathway) and Gln metabolism can induce redox stress, as evidenced by reduced mitochondrial membrane potential, elevated ROS levels, and inhibition of Gln degradation, and may be an effective therapeutic strategy for KRAS -driven NSCLC (82)

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