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Its formulation includes the active pharmaceutical ingredient tirzepatide along with pharmaceutical excipients necessary for stability and delivery, but it does not contain any vitamins, including vitamin B12 (cobalamin)

When documentation confirms intrinsic factor deficiency through Schilling test results, anti-intrinsic factor antibodies, or anti-parietal cell antibodies, D51.0 becomes the appropriate diagnostic code rather than the unspecified variant D51.9

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However, for patients without a true vitamin B12 deficiency, research shows that B12 injections are unlikely to boost energy or reduce fatigue