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Description
Formononetin attenuates A2535-induced cytotoxicity in HT22 cells via PI3K/Akt signaling and non-amyloidogenic cleavage of APP

Stosowany jest zarwno miejscowo jak i w iniekcjach podskrnych

General significance: It is important to note that the increases in the levels of pro-inflammatory cytokines are not only detrimental to the host due to the sequel that follow such as fever and cachexia, but also due to the alteration in the functions of immune cells

Biological evaluations included in vitro studies using neuroblastoma cells (SH-SY5Y) and human brain microvascular endothelial cells (HBMECs) to assess the ability of the nanoparticles to cross the BBB and effectively target neuronal cells
