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(2) the risk of FFA particle formation is further exacerbated when the increase in [mAb concentration] is not counteracted by an increase in the initial [PS20 concentration] to enhance the FFA-solubilizing capacity of the formulation

Misuse and abuse of amphetamine may cause increased heart rate, respiratory rate, or blood pressure

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This number is only larger for PD, with over a half (25) of the clinical trials taking place over the same 5-year period