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Aminotransferase elevations with omaveloxolone treatment in MOXIe Part 2 were transient, reversible after treatment discontinuation, and asymptomatic
Namely, KEAP1 is a redox biosensor utilizing reactivity of sulfur atoms, switching on the NRF2-mediated transcriptional activation of cytoprotective genes in response to the redox disturbance
[DOI] [PubMed] [Google Scholar] 65.Si D., Yin F., Peng J., Zhang G
