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13 Safety considerations and potential risks of probiotic use 13.1 The need for rigorous strain characterization Although probiotics are widely regarded as safe for the general population, their extensive use across diverse demographic groups, including infants, the elderly, and individuals with compromised immune function, necessitates rigorous and comprehensive safety assessments (53)

Through initiation of the empiric antibiotic algorithm, researchers found that the proportion of pulmonary exacerbations with antibiotic use consistent with the algorithm increased from 46.2% to 79.5%

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