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Description
In parallel, small molecules that enhance PGC-1 activity, such as ZLN005, can improve mitochondrial homeostasis in disease models in a manner that depends at least in part on PGC-1 (Zhu et al., 2022)

In addition to an increased incidence of hemolytic and thrombotic events, increased risk of cardiovascular disease development has been observed in previous studies

Present/absent variation (PAV) identification The program Nucmer in Mummer was used to compare two genomes, and then show-diff was utilized to identify PAVs

10, 11 The gene spans at least 23 kilobases of genomic DNA and consists of four exons and three introns, reflecting a simple structural organization that facilitates gene sequencing to genotype patients
