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Through the intensive study of the mechanical characteristics of native ECM in different tissues, researchers gradually began to explore the biomimetic biomechanical design of BNBMs in terms of cytocompatibility, proliferation and tissue repair for potential applications in modern TE and regenerative medicine [145147]
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84,90,91 Lactate buildup has the potential to stimulate gluconeogenesis in skeletal muscle and liver cells, converting lactate into glucose and subsequently releasing it into the bloodstream
