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136,137 This compensatory activation of AKT limits the efficacy of mTORC1-targeted therapies and underscores the rationale for using dual PI3K/mTOR or mTORC1/mTORC2 inhibitors to prevent feedback-driven survival signaling

Plant based food with carnitine Nuts (walnuts, peanuts, almonds, etc.) Avocado Beer yeast Wheat germ Carnitine supplements Although carnitine or acetyl-l-carnitine supplements can be taken, it is recommended to cover the needs of carnitine with a balanced diet

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Enzymes that play a crucial role in protecting cells against ROS include glutathione peroxidase, which facilitates the reduction of hydrogen peroxide and organic peroxides, superoxide dismutase (SOD), which helps in the conversion of superoxide radicals into hydrogen peroxide, and catalase (CAT), which helps in maintaining optimal levels of hydrogen peroxide within cells by neutralizing it