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Description
Several factors can cause a vitamin B12 deficiency

Factors such as individual risk assessment, potential side effects, timing of vaccination, and specific vaccine options need to be carefully evaluated

Long-term use of metformin (for type 2 diabetes) or proton pump inhibitors can also deplete B12 levels over time

[10] Enzyme-inducing anticonvulsants such as phenytoin, carbamazepine, and phenobarbital, as well as rifampicin, accelerate hepatic catabolism of vitamin D, shortening its half-life and potentially necessitating more frequent or higher intramuscular doses to sustain target 25-hydroxyvitamin D levels