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The antioxidant response genes activated by NRF2 include genes responsible for (a) regulating GSH synthesis and metabolism, (b) antioxidant proteins like GPX, (c) drug-metabolizing enzymes and xenobiotic transporters, and (d) additional stress response proteins (Jaramillo and Zhang, 2013)

For long-term maintenance, most healthcare providers recommend one B12 injection every 4 to 12 weeks

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B12 shots FAQs What does a B12 shot do for you