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5 Anti-inflammatory agents, such as IL-6 antagonists (ALD518), IL-6R inhibitors (tocilizumab), and dual-target agents (OHR/AVR118), have been shown to stabilize body weight and reduce inflammation

Histological and immunohistochemical staining of cardiac sections from the untreated (without sFRP-4) rats indicated that following I/R injury, the left ventricular wall thickness decreased, left ventricular cavity size significantly increased, deactivated GSK-3 levels increased, and -catenin activity was upregulated

System Xc-is an important antioxidant system involved in the regulation of ferroptosis

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